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Horizon Europe Cluster 1 Health — 2027 calls (HORIZON-HLTH-2027-01 and HORIZON-HLTH-2027-02)

On 29 October 2026 the European Commission opens the 2027 Horizon Europe health calls: 14 topics, €528.2 million in total, between €3 and €11 million per project. International research consortia, hospitals, companies and public authorities can apply. Deadline: 17 February 2027.

Who can apply
International consortia made up of universities, hospitals, research institutes and companies
Total budget
528.2 million
Funding amount
Between 3 and 11 million
Submission period
29 October 2026 – 17 February 2027 (single-stage call and stage 1); stage 2 until 16 September 2027

Checked against official sources on · funder: European Commission · official source

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The guide has not been published yet, but good applications are built before launch. Those who start when the call window opens usually miss out on it.

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Horizon Europe Health 2027: €528 million across 14 topics, opening on 29 October

Who can apply

International consortia made up of universities, hospitals, research institutes and companies. SME participation is encouraged. Organisations from Romania can be partners or coordinators, under the conditions set out in the general annexes to the work programme. For topics DISEASE-10 and DISEASE-07, entities from the USA can also receive funding. For the pre-commercial procurement topic ENVHLTH-MISSCLIMA-03, the consortium may include hospitals, care services, municipalities, civil protection and government agencies.

What it covers

  • Cell-free protein synthesis platforms for biological medicines (IND-01, €24.5 million)
  • Small-molecule antivirals for pathogens with epidemic potential (DISEASE-05) and monoclonal antibodies against flaviviruses and other viruses (DISEASE-06, DISEASE-07)
  • New antimicrobials against resistant pathogens (DISEASE-08)
  • Prevention and management of chronic non-communicable diseases in children and young people (DISEASE-10) and innovative interventions for non-communicable diseases (DISEASE-01, two stages)
  • Reducing adverse reactions in patients taking multiple medicines (CARE-02)
  • Disabilities across the life course and independent living (STAYHLTH-01)
  • Climate-related exposures and the human exposome (ENVHLTH-02); tools for adapting health to climate change, through pre-commercial procurement (ENVHLTH-MISSCLIMA-03)
  • AI-developed predictive biomarkers for chronic non-communicable diseases (TOOL-01) and clinical studies for neurodegenerative diseases (DISEASE-14)
Full analysis Horizon Europe Health 2027: €528 million across 14 topics, opening on 29 October Conditions, steps and pitfalls, with official sources →

We prepare your application before the window opens

  1. We analyse whether you qualify and under which programme exactly.
  2. We build the application: business plan, budget, supporting documents.
  3. We submit during the call window and follow the evaluation.
  4. We stay with you through the reimbursement file and final payment.

Frequently asked questions

When can projects be submitted to the Horizon Europe Health 2027 calls?

The calls HORIZON-HLTH-2027-01 and HORIZON-HLTH-2027-02 open on 29 October 2026. For single-stage topics and for stage 1 of the two-stage topics, the deadline is 17 February 2027. Full proposals for stage 2 must be submitted by 16 September 2027.

What budget do the 2027 Cluster 1 Health calls have?

In total €528.2 million. The single-stage call HORIZON-HLTH-2027-01 has €341.6 million for 10 topics, and the two-stage call HORIZON-HLTH-2027-02 has €186.6 million for 4 topics.

How much funding can a project receive?

Between €3 million and €11 million per project, depending on the topic. For example: €3–4 million for chronic diseases in children and young people, €6–8 million for cell-free protein synthesis platforms, €9–11 million for antivirals and €10–11 million for the exposome and climate.

Can a company or hospital from Romania apply?

Yes. Organisations from EU Member States, including Romania, can take part as partners or coordinators in international consortia, under the eligibility conditions in the general annexes to the work programme. SME participation is explicitly encouraged.

What does the "blind" evaluation in stage 1 mean?

For the two-stage topics, stage 1 proposals are evaluated without identifying the applicants. The summary and Part B must not include organisation names, acronyms, logos or the names of team members.

What type of funding is awarded?

Most topics are research and innovation actions (RIA). Point-of-care diagnostics (IND-02) is an innovation action (IA), and adapting health systems to climate (ENVHLTH-MISSCLIMA-03) is a pre-commercial procurement (PCP). The topics in the two-stage call use lump sum grants.

How long does it take to prepare the application?

It depends on the complexity of the project and the documents you already have. The first step is the eligibility analysis, which tells you what needs to be prepared.

What happens if I do not qualify?

We tell you before any contract is signed, and if another suitable programme exists, we point you to it.

Next step

We prepare your application before it opens — Horizon Europe Cluster 1 Health — 2027 calls (HORIZON-HLTH-2027-01 and HORIZON-HLTH-2027-02)

Fill in the form and we will tell you whether you qualify. If you do not qualify under this programme, we will tell you which other one you could apply for — or that there is none, if that is the case.

or call us directly on 0755 167 167

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